Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 6/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 5/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | IL1B | P01584 | 2/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25325674 | 0.99 | MAP1LC3B (0.59) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL25905191 | 0.93 | MAP1LC3B (0.66) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| Hydrochloric Acid SCHEMBL25327075 | 0.92 | MAP1LC3B (0.65) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL26814272 | 0.87 | MAP1LC3B (0.63) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL26814240 | 0.87 | MAP1LC3B (0.63) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL25327072 | 0.86 | MAP1LC3B (0.59) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL26840009 | 0.86 | MAP1LC3B (0.62) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL22276670 | 0.85 | STAT3 (0.57) | STAT3CRBNDDB1 | |
| SCHEMBL17536588 | 0.85 | STAT3 (0.66) | MAP1LC3BSTAT3TNFCRBNIKZF3 | |
| SCHEMBL26661839 | 0.84 | MAP1LC3B (0.63) | MAP1LC3BSTAT3TNFCRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144053-A1 | HETEROCYCLIC DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-08-03 | — | — | WO | disclosed |