SCHEMBL25905404

SCHEMBL25905404

c1ccc(-c2nc3ccc(-c4ccc5[nH]cnc5c4)cc3[nH]2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.55
RAB9A P51151 5/20 0.55
KDM4E B2RXH2 4/20 0.55
ALDH1A1 P00352 4/20 0.55
HPGD P15428 4/20 0.55
MAPT P10636 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
TP53 P04637 3/20 0.55
HSD17B10 Q99714 3/20 0.55
GAA P10253 2/20 0.55
GLA P06280 1/20 0.55
HTT P42858 1/20 0.55
GFER P55789 1/20 0.55
RCE1 Q9Y256 1/20 0.55
MEN1 O00255 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
KMT2A Q03164 1/20 0.55
FTO Q9C0B1 1/20 0.55
DGAT1 O75907 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20847438 0.92 QPCT (0.58) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL459808 0.92 NPC1 (0.54) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL18806843 0.89 MEN1 (0.52) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL24684965 0.88 QPCT (0.52) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL14669372 0.87 NPC1 (0.49) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL14669311 0.87 QPCT (0.57) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL16281922 0.85 NPC1 (0.66) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL13299660 0.85 NPC1 (0.72) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL1459333 0.85 NPC1 (0.56) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL14859469 0.84 NPC1 (0.52) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146885-A1 FUNCTIONALIZED POLYBENZIMIDAZOLE POLYMERS FOR IONOMER AND PROTON EXCHANGE MEMBRANE APPLICATIONS 1S1 ENERGY, INC. (US) 2023-08-03 WO disclosed