Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669372 | 0.96 | NPC1 (0.49) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL25905404 | 0.92 | NPC1 (0.55) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL2686936 | 0.88 | NPC1 (0.54) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL14665660 | 0.88 | NPC1 (0.44) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL1459333 | 0.87 | NPC1 (0.56) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL417622 | 0.87 | MAPT (0.55) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL2569383 | 0.87 | NPC1 (0.56) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL30822560 | 0.87 | NPC1 (0.56) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL18806843 | 0.86 | MEN1 (0.52) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL22649095 | 0.86 | NPC1 (0.67) | NPC1RAB9AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885870-A1 | Carbonylation process | BP Chemicals Limited (GB) | 1998-12-23 | — | — | EP | claimed |
| WO-2012102923-A2 | POROUS POLYBENZIMIDAZOLE RESIN AND METHOD OF MAKING SAME | PBI PERFOMANCE PRODUCTS, INC. (US) | 2012-08-02 | — | — | WO | disclosed |
| WO-2011163158-A2 | PBI/EPOXY COATINGS | PBI PERFORMANCE PRODUCTS, INC. (US) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011137131-A1 | POLYBENZIMIDAZOLE-BASED MEMBRANES FOR THE DEHYDRATION OF ORGANIC LIQUIDS VIA PERVAPORATION | PBI PERFORMANCE PRODUCTS, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| EP-0057492-A2 | Process for the surface modification of carbon fibres | BASF Aktiengesellschaft (DE) | 1982-08-11 | — | — | EP | disclosed |