Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.52 |
| ▸ | PLA2G2E | Q9NZK7 | 6/20 | 0.52 |
| ▸ | PLA2G5 | P39877 | 5/20 | 0.52 |
| ▸ | PLA2G2F | Q9BZM2 | 3/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 3/20 | 0.52 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.52 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.52 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.52 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862634 | 0.94 | PLA2G2A (0.49) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL818833 | 0.94 | PLA2G2A (0.49) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7954700 | 0.92 | PLA2G2A (0.56) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL8053035 | 0.92 | PLA2G2A (0.48) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7966553 | 0.90 | PLA2G2A (0.45) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7966510 | 0.89 | PLA2G2A (0.51) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL819162 | 0.89 | PLA2G2A (0.49) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7965994 | 0.88 | PLA2G2A (0.44) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7966103 | 0.88 | PLA2G2A (0.54) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7967324 | 0.88 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3220902-A2 | ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS | Ophirex, Inc. (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2013067579-A1 | ADIPOSITY-MODULATING MOLECULES AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-05-16 | — | — | WO | disclosed |
| WO-2011137390-A1 | TREATMENT OF MAJOR ADVERSE CARDIAC EVENTS AND ACUTE CORONARY SYNDROME IN DIABETIC PATIENTS USING SECRETORY PHOSPHOLIPASE A2 (SPLA2) INHIBITOR OR SPLA2 INHIBITOR COMBINATION THERAPIES | ANTHERA PHARMACEUTICALS, INC. (US) | 2011-11-03 | — | — | WO | disclosed |