⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277283 | 0.70 | ALDH1A1 (0.54) | — | |
| SCHEMBL253206 | 0.70 | — | — | |
| SCHEMBL6474155 | 0.69 | — | — | |
| SCHEMBL10495054 | 0.67 | ALDH1A1 (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL8813878 | 0.67 | ALDH1A1 (0.50) | — | |
| Hydrazine SCHEMBL23925260 | 0.67 | — | — | |
| SCHEMBL10821490 | 0.67 | ALDH1A1 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL7271342 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL4917852 | 0.67 | — | — | |
| Methane SCHEMBL9323244 | 0.67 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850135-A | Sulfur-containing Janus type ionizable liposome and application thereof | 喻国灿 | 2023-03-28 | — | — | CN | claimed |
| CN-115515925-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115515926-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115197078-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-115197080-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-115197079-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| WO-2022214026-A1 | PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-13 | — | — | WO | claimed |
| WO-2022214025-A1 | PEGYLATED LIPID, LIPOSOME MODIFIED THEREBY, PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME, PREPARATION THEREOF, AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-13 | — | — | WO | claimed |
| CN-115010915-A | Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative | 厦门赛诺邦格生物科技股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113429559-A | Six-arm polyethylene glycol derivative with end hetero-functionalized and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-112694608-A | Six-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2021-04-23 | — | — | CN | claimed |
| CN-110643032-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-115850135-A | Sulfur-containing Janus type ionizable liposome and application thereof | 喻国灿 | 2023-03-28 | — | — | CN | disclosed |
| CN-113402405-B | Cationic lipid, liposome containing cationic lipid, nucleic acid pharmaceutical composition containing liposome, preparation and application thereof | 厦门赛诺邦格生物科技股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115010915-A | Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative | 厦门赛诺邦格生物科技股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| US-20130172323-A1 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| EP-2566864-A2 | PYRIDAZINONES AS GPR119 AGONISTS | Boehringer Ingelheim International GmbH (DE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138427-A2 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| US-4576629-A | Herbicidal thiadiazole ureas | UNION CARBIDE CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |