SCHEMBL2590619

SCHEMBL2590619

CCCCCCCCCCCCCC(N)(N)C(O)C(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.44
SPHK1 Q9NYA1 2/20 0.44
LMNA P02545 2/20 0.44
GMNN O75496 1/20 0.44
POLB P06746 1/20 0.44
THPO P40225 1/20 0.44
MTOR P42345 1/20 0.44
BLM P54132 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
CETP P11597 1/20 0.44
HTT P42858 1/20 0.44
UBE2N P61088 1/20 0.44
SMPD1 P17405 4/20 0.40
FDPS P14324 2/20 0.40
TNNC1 P63316 5/20 0.38
S1PR1 P21453 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7867569 1.00 CYP2D6 (0.44) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL28400584 0.80 SMPD1 (0.41) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL4294189 0.80 LMNA (0.42) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL10767247 0.78 LMNA (0.41) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL13730862 0.77 CYP2D6 (0.41) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL28367954 0.75 CYP2D6 (0.40) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL28367467 0.75 CYP2D6 (0.40) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL28446431 0.74 LMNA (0.37) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL31738650 0.74 CYP2D6 (0.38) CYP2D6SPHK1LMNAGMNNPOLB
SCHEMBL29199484 0.74 CYP2D6 (0.38) CYP2D6SPHK1LMNAGMNNPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3554498-A1 METHODS OF TREATING HYPERPIGMENTATION DISORDERS Chromaderm, Inc. (US) 2019-10-23 EP disclosed
CN-110198701-A Cosmetic composition containing quinone and its topical use on skin and hair 瑞派若基恩集团 2019-09-03 CN disclosed
WO-2018118874-A1 METHODS OF TREATING HYPERPIGMENTATION DISORDERS CHROMADERM, INC. (US) 2018-06-28 WO disclosed
WO-2015038951-A1 TOPICAL COMPOUNDS CONTAINING ADIPOSE-DERIVED HORMONES FOR THE REJUVENATION OF SKIN OHIO STATE INNOVATION FOUNDATION (US) 2015-03-19 WO disclosed
WO-2012056471-A2 NOVEL PROCESS FOR PREPARING DEXIBUPROFEN READY TO COMPRESS GRANULES SHASUN PHARMACEUTICALS LIMITED (IN) 2012-05-03 WO disclosed
WO-2011135591-A2 NOVEL TABLET COMPOSITION OF POLYALLYLAMINE POLYMERS SHASUN PHARMACEUTICALS LIMITED (IN) 2011-11-03 WO disclosed
EP-0885000-A2 TOPICAL COMPOSITIONS COMPRISING AN OIL-IN-WATER EMULSION AND A RETINOID Johnson & Johnson Consumer Companies, Inc. (US) 1998-12-23 EP disclosed
WO-1997031620-A2 TOPICAL COMPOSITIONS COMPRISING AN OIL-IN-WATER EMULSION AND A RETINOID JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 1997-09-04 WO disclosed
WO-1996007396-A9 RETINOID COMPOSITIONS 1996-09-06 WO disclosed
WO-1996007396-A2 RETINOID COMPOSITIONS JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 1996-03-14 WO disclosed