Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.47 |
| ▸ | GRM6 | O15303 | 2/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206267 | 0.87 | GSR (0.60) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL136970 | 0.87 | GSR (0.60) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL2593867 | 0.86 | CHRM2 (0.39) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL3951755 | 0.80 | KMT2A (0.55) | GSRCYP1A2GRM8GRM6GRM7 | |
| Glutamic Acid SCHEMBL7821241 | 0.78 | GRM8 (0.72) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL542836 | 0.75 | GRM8 (0.82) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL29373318 | 0.75 | GRM8 (0.82) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL27950028 | 0.75 | GRM8 (0.82) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL839697 | 0.75 | GRM8 (0.82) | GSRCYP1A2GRM8GRM6GRM7 | |
| SCHEMBL542624 | 0.75 | GRM8 (0.82) | GSRCYP1A2GRM8GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227503-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2023-07-20 | — | — | US | disclosed |
| US-20190010191-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2019-01-10 | — | — | US | disclosed |
| US-20170260235-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | UNIVERSITE PAUL SABATIER (TOULOUSE III) (FR) | 2017-09-14 | — | — | US | disclosed |
| US-9617307-B2 | Polypeptide expressed in the stratum corneum and use thereof | UNIVERSITE PAUL SABATIER (TOULOUSE III) (FR) | 2017-04-11 | — | — | US | disclosed |
| US-20150299260-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-10-22 | — | — | US | disclosed |
| US-9085635-B2 | Polypeptide expressed in the stratum corneum and thereof | CHANEL PARFUMS BEAUTE (FR) | 2015-07-21 | — | — | US | disclosed |
| EP-2563807-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | Chanel Parfums Beauté (FR) | 2013-03-06 | — | — | EP | disclosed |
| US-20130053327-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | CHANEL PARFUMS BEAUTE (FR) | 2013-02-28 | — | — | US | disclosed |
| WO-2011135253-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | CHANEL PARFUMS BEAUTE (FR) | 2011-11-03 | — | — | WO | disclosed |
| US-4916070-A | Fibrin-specific antibodies and method of screening for the antibodies | THE GENERAL HOSPITAL CORPORATION (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0249007-A2 | A method of screening hybridomas | THE GENERAL HOSPITAL CORPORATION (US) | 1987-12-16 | — | — | EP | disclosed |
| WO-1987006263-A1 | FIBRIN-SPECIFIC ANTIBODIES AND METHOD OF SCREENING FOR THE ANTIBODIES | THE GENERAL HOSPITAL CORPORATION (US) | 1987-10-22 | — | — | WO | disclosed |