Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590627 | 0.86 | GSR (0.47) | ALOX15BLMPMP22KMT2ANFKB1 | |
| SCHEMBL3951755 | 0.80 | KMT2A (0.55) | ALOX15BLMPMP22KMT2ANFKB1 | |
| SCHEMBL1509733 | 0.77 | ALOX15 (0.43) | ALOX15BLMPMP22KMT2ACYP2D6 | |
| SCHEMBL28041162 | 0.77 | ALOX15 (0.33) | ALOX15BLMPMP22KMT2ACYP2D6 | |
| SCHEMBL8051398 | 0.74 | GSR (0.44) | CHRM2CHRM4CHRM1ALOX15BLM | |
| SCHEMBL10940176 | 0.72 | — | — | |
| SCHEMBL10944752 | 0.72 | — | — | |
| SCHEMBL11322855 | 0.71 | CYP2D6 (0.34) | CYP2D6NFKB1LMNAMAPT | |
| SCHEMBL136970 | 0.71 | GSR (0.60) | ALOX15BLMPMP22KMT2ANFKB1 | |
| SCHEMBL22206267 | 0.71 | GSR (0.60) | ALOX15BLMPMP22KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563807-B1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2016-10-19 | — | — | EP | disclosed |
| EP-2563807-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | Chanel Parfums Beauté (FR) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011135253-A1 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF | CHANEL PARFUMS BEAUTE (FR) | 2011-11-03 | — | — | WO | disclosed |