SCHEMBL25906703

SCHEMBL25906703

Cc1cc2c(c(C)c1F)CC(C)CC2

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP2A6 P11509 2/20 0.38
CYP2A13 Q16696 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 2/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
THRB P10828 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037 0.88 CYP2A6 (0.39) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL26545164 0.88 CYP2A6 (0.39) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL21891623 0.88 CYP2A6 (0.39) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL18269911 0.86 ALDH1A1 (0.38) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL21096538 0.75 CYP2A6 (0.33) ALDH1A1CYP2A6CYP2A13TSHR
SCHEMBL12433446 0.74 CYP2A6 (0.35) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL14525633 0.74 ALDH1A1 (0.42) ALDH1A1CYP2A6CYP2A13TSHRKDM4E
SCHEMBL19221798 0.72 TRPV1 (0.36) ALDH1A1CYP2A6CYP2A13TSHRMAPT
SCHEMBL14582425 0.71 HTR2A (0.35) ALDH1A1CYP2A6CYP2A13TSHR
SCHEMBL13218790 0.71 ALDH1A1 (0.36) ALDH1A1CYP2A6CYP2A13TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3839008-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-07-26 EP disclosed