⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732188 | 0.71 | EBP (0.34) | — | |
| SCHEMBL15317981 | 0.70 | — | — | |
| SCHEMBL27281267 | 0.70 | — | — | |
| SCHEMBL18909247 | 0.70 | — | — | |
| SCHEMBL25907261 | 0.69 | — | — | |
| SCHEMBL22030929 | 0.65 | SSTR3 (0.31) | — | |
| SCHEMBL17778030 | 0.64 | — | — | |
| SCHEMBL17778023 | 0.64 | — | — | |
| SCHEMBL12832677 | 0.64 | — | — | |
| SCHEMBL25554775 | 0.64 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |