⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050242 | 0.70 | — | — | |
| SCHEMBL25907170 | 0.69 | — | — | |
| SCHEMBL21618649 | 0.67 | CYP2D6 (0.34) | — | |
| SCHEMBL25907165 | 0.67 | GAA (0.30) | — | |
| SCHEMBL24134112 | 0.62 | — | — | |
| SCHEMBL20797070 | 0.60 | — | — | |
| SCHEMBL25978353 | 0.60 | — | — | |
| SCHEMBL11896737 | 0.60 | — | — | |
| SCHEMBL25332801 | 0.59 | MTNR1A (0.39) | — | |
| SCHEMBL25948458 | 0.59 | MTNR1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |