⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975339 | 0.79 | — | — | |
| SCHEMBL22151877 | 0.69 | — | — | |
| SCHEMBL21771604 | 0.67 | APLNR (0.32) | — | |
| SCHEMBL26027218 | 0.67 | — | — | |
| SCHEMBL26022032 | 0.66 | — | — | |
| SCHEMBL26032327 | 0.66 | — | — | |
| SCHEMBL8270227 | 0.64 | APLNR (0.48) | — | |
| SCHEMBL25859517 | 0.64 | — | — | |
| SCHEMBL25160372 | 0.63 | — | — | |
| SCHEMBL20121061 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |