Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.46 |
| ▸ | SIK1 | P57059 | 1/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898542 | 0.90 | TIPARP (0.48) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25899141 | 0.89 | TIPARP (0.47) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25897832 | 0.89 | TIPARP (0.49) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL26793446 | 0.88 | TIPARP (0.49) | TIPARPTNFKDM4ELMNAMAPT | |
| SCHEMBL26787784 | 0.88 | TIPARP (0.44) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25908053 | 0.87 | TIPARP (0.45) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25907205 | 0.87 | TIPARP (0.47) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25902196 | 0.86 | TIPARP (0.46) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25901729 | 0.86 | TIPARP (0.54) | TIPARPSIK1SIK2SIK3TNF | |
| SCHEMBL25900117 | 0.85 | TIPARP (0.46) | TIPARPTNFLMNASMN1; SMN2DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |