Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.54 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | SIK1 | P57059 | 1/20 | 0.31 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.31 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907205 | 0.89 | TIPARP (0.47) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25898542 | 0.88 | TIPARP (0.48) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25908352 | 0.87 | TIPARP (0.49) | TIPARPTNF | |
| SCHEMBL25902196 | 0.87 | TIPARP (0.46) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25908010 | 0.87 | TIPARP (0.65) | TIPARPTNF | |
| SCHEMBL25897832 | 0.87 | TIPARP (0.49) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25907789 | 0.86 | TIPARP (0.46) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL26793446 | 0.86 | TIPARP (0.49) | TIPARPTNF | |
| SCHEMBL25908053 | 0.83 | TIPARP (0.45) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25900117 | 0.81 | TIPARP (0.46) | TIPARPTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |