Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 18/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278706 | 1.00 | ATR (0.38) | ATRCYP4F2CYP4A11 | |
| SCHEMBL25907404 | 0.82 | CHEK1 (0.34) | ATR | |
| SCHEMBL25908530 | 0.81 | CYP4F2 (0.39) | ATRCYP4F2CYP4A11 | |
| SCHEMBL30662635 | 0.80 | ATR (0.34) | ATRCYP4F2CYP4A11 | |
| SCHEMBL25908700 | 0.79 | ATR (0.42) | ATRCYP4F2CYP4A11 | |
| SCHEMBL26199500 | 0.79 | ATR (0.49) | ATR | |
| SCHEMBL24961989 | 0.78 | CYP4F2 (0.41) | ATRCYP4F2CYP4A11 | |
| SCHEMBL26199499 | 0.78 | ATR (0.48) | ATR | |
| SCHEMBL25160000 | 0.78 | ATR (0.50) | ATR | |
| SCHEMBL25907412 | 0.75 | CHEK1 (0.35) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |