Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190837 | 0.86 | HSD11B1 (0.47) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL1057481 | 0.83 | HSD11B1 (0.41) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL12548366 | 0.83 | HSD11B1 (0.41) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL1057478 | 0.83 | HSD11B1 (0.41) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL28804055 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL28804053 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1USP30KAT6AKAT8 | |
| SCHEMBL228179 | 0.81 | HSD11B1 (0.46) | HSD11B1ASGR1KDM4DALDH1A1CHRM3 | |
| SCHEMBL12256701 | 0.81 | MEN1 (0.49) | HSD11B1USP30ALDH1A1 | |
| SCHEMBL2394686 | 0.81 | MEN1 (0.49) | HSD11B1USP30ALDH1A1 | |
| SCHEMBL1344888 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1USP30KDM4DBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219485-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-02 | — | — | EP | disclosed |