Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15829966 | 0.84 | POLB (0.54) | EPHX2HPGDL3MBTL1 | |
| SCHEMBL15829967 | 0.81 | EPHX2 (0.54) | EPHX2L3MBTL1 | |
| SCHEMBL5969516 | 0.81 | EPHX2 (0.54) | EPHX2L3MBTL1CTDSP1TDP1 | |
| SCHEMBL23734883 | 0.79 | HTT (0.54) | EPHX2HPGDHSD11B1MGLLHTT | |
| SCHEMBL8360507 | 0.79 | HPGD (0.73) | HPGDHSD11B1HTTL3MBTL1 | |
| SCHEMBL23417314 | 0.78 | HPGD (0.64) | EPHX2HPGDHSD11B1MGLLHTT | |
| SCHEMBL15829991 | 0.76 | SSTR1 (0.48) | EPHX2HPGDL3MBTL1 | |
| SCHEMBL16220683 | 0.76 | EPHX2 (0.52) | EPHX2L3MBTL1CTDSP1TDP1 | |
| SCHEMBL15829846 | 0.76 | EPHX2 (0.52) | EPHX2L3MBTL1CTDSP1TDP1 | |
| SCHEMBL15830341 | 0.76 | EPHX2 (0.52) | EPHX2L3MBTL1CTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |