Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22772044 | 0.81 | EPHX2 (0.60) | HTTL3MBTL1EPHX2HPGDRHOA | |
| SCHEMBL3579474 | 0.80 | SPR (0.48) | GFERHCRTR1KMT2A | |
| SCHEMBL3579476 | 0.80 | SPR (0.48) | GFERHCRTR1KMT2A | |
| SCHEMBL279836 | 0.80 | EPHX2 (0.59) | HTTL3MBTL1EPHX2HPGDRHOA | |
| SCHEMBL15829846 | 0.79 | EPHX2 (0.52) | L3MBTL1EPHX2CTDSP1TDP1KMT2A | |
| SCHEMBL16220683 | 0.79 | EPHX2 (0.52) | L3MBTL1EPHX2CTDSP1TDP1KMT2A | |
| SCHEMBL15830341 | 0.79 | EPHX2 (0.52) | L3MBTL1EPHX2CTDSP1TDP1KMT2A | |
| SCHEMBL25909077 | 0.79 | EPHX2 (0.53) | HTTL3MBTL1EPHX2HPGDCTDSP1 | |
| SCHEMBL22735588 | 0.77 | HTT (0.51) | HTTL3MBTL1EPHX2HPGDRHOA | |
| SCHEMBL23734969 | 0.77 | HTT (0.51) | HTTL3MBTL1EPHX2HPGDRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594202-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-11 | — | — | EP | disclosed |