Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 5/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25915014 | 0.90 | P2RX1 (0.37) | P2RX1P2RX3P2RX4TMPRSS2POLRMT | |
| SCHEMBL24917308 | 0.89 | P2RX1 (0.38) | P2RX1P2RX3P2RX4TMPRSS2POLRMT | |
| SCHEMBL24339537 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24339534 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24339773 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24339481 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24340365 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24407353 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL24339857 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 | |
| SCHEMBL25956367 | 0.88 | TMPRSS2 (0.42) | TMPRSS2POLRMTADKENTPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12102648-B2 | Orally-bioavailable nucleoside analogs | VenatoRx Pharmaceuticals, Inc. (US) | 2024-10-01 | — | — | US | disclosed |
| EP-4355755-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | Venatorx Pharmaceuticals, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-07-27 | — | — | US | disclosed |
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-07-27 | — | — | US | disclosed |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | VenatoRx Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | VenatoRx Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | P2RX1 1143/4885P2RX3 1893/4885P2RX4 1460/4885 |
| US-12102648-B2 | Orally-bioavailable nucleoside analogs | SLC29A2, SLC29A1, PNP | P2RX1 1143/4885P2RX3 1893/4885P2RX4 1460/4885 |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | SLC29A2, SLC29A1, PNP | P2RX1 1143/4885P2RX3 1893/4885P2RX4 1460/4885 |
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | P2RX1 1143/4885P2RX3 1893/4885P2RX4 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.