SCHEMBL24339773

SCHEMBL24339773

CCCCCCCCCCCCCCCCOCCOP(=O)(O)OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.42
▸ ADK P55263 6/20 0.36
▸ POLRMT O00411 1/20 0.35
▸ ENTPD1 P49961 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24339857 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24407353 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24340365 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL25956367 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24339537 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24339481 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24339534 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTENTPD1
SCHEMBL24304364 0.98 TMPRSS2 (0.42) TMPRSS2ADKPOLRMT
SCHEMBL25967624 0.98 TMPRSS2 (0.42) TMPRSS2ADKPOLRMT
SCHEMBL25968060 0.98 TMPRSS2 (0.42) TMPRSS2ADKPOLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12208110-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-01-28 — — US disclosed
US-11963967-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-04-23 — — US disclosed
EP-4228685-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-08-23 — — EP disclosed
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-05-12 — — US disclosed
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-05-12 — — US disclosed
WO-2022081973-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-04-21 — — WO disclosed
WO-2022081973-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 320/4885ADK 1209/4885POLRMT 361/4885
US-12208110-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS1, SGMS2 TMPRSS2 162/4885ADK 2196/4885POLRMT 455/4885
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 320/4885ADK 1209/4885POLRMT 361/4885
US-11963967-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 TMPRSS2 320/4885ADK 1209/4885POLRMT 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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