Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23977436 | 0.81 | AR (0.44) | PTGDR2ALDH1A1KDM4EAR | |
| SCHEMBL3536980 | 0.81 | PTGDR2 (0.51) | PTGDR2MAOBALDH1A1KDM4EGAA | |
| SCHEMBL30225422 | 0.81 | PTGDR2 (0.40) | PTGDR2MAOBNCEH1ALDH1A1KDM4E | |
| SCHEMBL23977315 | 0.81 | PTGDR2 (0.40) | PTGDR2MAOBNCEH1ALDH1A1KDM4E | |
| SCHEMBL7067974 | 0.77 | TSHR (0.53) | PTGDR2MAOBNCEH1ALDH1A1KDM4E | |
| SCHEMBL24227108 | 0.76 | CA12 (0.41) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL5780141 | 0.74 | MRGPRX4 (0.49) | PTGDR2MAOBNCEH1ALDH1A1KDM4E | |
| SCHEMBL23614061 | 0.73 | TNFSF11 (0.50) | NCEH1ALDH1A1KDM4EGAATSHR | |
| SCHEMBL3541792 | 0.73 | NCEH1 (0.47) | PTGDR2MAOBNCEH1ALDH1A1KDM4E | |
| SCHEMBL11673708 | 0.73 | TSHR (0.57) | ALDH1A1KDM4EGAATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | HDAC6, Q6ZSR9, MON2 | PTGDR2 4418/4885MAOB 916/4885NCEH1 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.