Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909467 | 0.81 | PTGDR2 (0.41) | ARALDH1A1KDM4EPTGDR2 | |
| SCHEMBL2094284 | 0.81 | ALDH1A1 (0.63) | ARALDH1A1KDM4EUSP2ESRRA | |
| SCHEMBL16951586 | 0.80 | AR (0.49) | ARALDH1A1KDM4EUSP2ESRRA | |
| SCHEMBL1798639 | 0.77 | AR (0.44) | ARALDH1A1KDM4EUSP2ESRRA | |
| SCHEMBL1798728 | 0.76 | AR (0.49) | ARALDH1A1KDM4EUSP2ESRRA | |
| SCHEMBL1799535 | 0.75 | AR (0.42) | ARALDH1A1KDM4EUSP2KDM1A | |
| SCHEMBL509522 | 0.73 | AR (0.66) | ARALDH1A1KDM4EUSP2KDM1A | |
| SCHEMBL29490258 | 0.73 | AR (0.66) | ARALDH1A1KDM4EUSP2KDM1A | |
| SCHEMBL4669307 | 0.72 | ALDH1A1 (0.53) | ARALDH1A1KDM4EUSP2ESRRA | |
| SCHEMBL11616908 | 0.71 | KDM1A (0.56) | ARALDH1A1KDM4EUSP2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |