SCHEMBL25909499

SCHEMBL25909499

CC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.51
▸ POLRMT O00411 1/20 0.33
▸ PIK3CD O00329 4/20 0.32
▸ ADK P55263 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gs-441524 SCHEMBL31174011 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL15998246 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL22663744 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL23870459 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL10120691 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL24975226 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL22142944 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL24667691 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL22096285 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL10120689 0.90 TMPRSS2 (0.60) TMPRSS2POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355649-A1 FORMULATIONS OF ANTI-VIRAL COMPOUNDS SAYVAA PHARMACEUTICALS INC. 2023-11-09 — — US disclosed
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. 2023-07-27 — — US disclosed
US-11638715-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2023-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355649-A1 FORMULATIONS OF ANTI-VIRAL COMPOUNDS SARS1, RNMT, NSUN2 TMPRSS2 1436/4885POLRMT 53/4885PIK3CD 1662/4885
US-11638715-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP TMPRSS2 100/4885POLRMT 138/4885PIK3CD 3488/4885
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS SLC29A2, SLC29A1, PNP TMPRSS2 100/4885POLRMT 138/4885PIK3CD 3488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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