Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631710 | 0.78 | CYP2E1 (0.36) | LMNAMAPTALOX5CYP2E1CYP2A6 | |
| SCHEMBL28631713 | 0.78 | CYP2E1 (0.36) | LMNAMAPTALOX5CYP2E1CYP2A6 | |
| SCHEMBL28924463 | 0.78 | CYP2E1 (0.36) | LMNAMAPTALOX5CYP2E1CYP2A6 | |
| SCHEMBL726321 | 0.78 | ESR1 (0.58) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL726320 | 0.78 | ESR1 (0.58) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL1225178 | 0.78 | ESR1 (0.58) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL2992596 | 0.77 | MAPT (0.39) | LMNAMAPTALOX5NPC1RAB9A | |
| SCHEMBL7803180 | 0.73 | ESR1 (0.64) | ESR1ESR2MAPTALOX5PTGS1 | |
| SCHEMBL23204347 | 0.72 | — | — | |
| SCHEMBL3296577 | 0.72 | AKR1C3 (0.57) | LMNAMAPTALOX5LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241597-A1 | PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS | TEXAS TECH UNIVERSITY SYSTEM | 2023-08-03 | — | — | US | disclosed |
| US-20230241597-A1 | PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS | TEXAS TECH UNIVERSITY SYSTEM | 2023-08-03 | — | — | US | disclosed |