Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726321 | 1.00 | ESR1 (0.58) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL1225178 | 1.00 | ESR1 (0.58) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL7803180 | 0.95 | ESR1 (0.64) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| Diphenylamine SCHEMBL10746269 | 0.88 | ALDH1A1 (0.47) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL9806375 | 0.87 | ESR1 (0.55) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL4602278 | 0.87 | MAPT (0.59) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL8089190 | 0.87 | ESR1 (0.80) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL6547576 | 0.87 | ESR1 (0.55) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL9806371 | 0.87 | ESR1 (0.55) | ESR1ESR2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL8712456 | 0.87 | ESR1 (0.80) | ESR1ESR2ALDH1A1NQO2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280245-A1 | 3-Aryl-6-aryl-[1,2,4]triazolo[4,3-alpha]pyridines as Inhibitors of Cell Proliferation and the Use Thereof | IMPACT THERAPEUTICS, INC. (CN) | 2013-10-24 | — | — | US | claimed |
| US-7008990-B2 | Use of polymeric reaction product | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-07 | — | — | US | claimed |
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |
| EP-1144470-B1 | THERMALLY STABLE POLYETHERAMINES | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-11-30 | — | — | EP | claimed |
| US-20040034182-A1 | Method for the production of a polymerisation reaction product | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-19 | — | — | US | claimed |
| US-20030170306-A1 | Use of polymeric reaction product | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-11 | — | — | US | claimed |
| US-6589621-B1 | A blend of an inorganic base, an organic base, a monofunctional organic nucleophile or a multifunctional organic nucleophile and a thermoplastic hydroxy-functionalized polyetheramine | DOW GLOBAL TECHNOLOGIES INC. | 2003-07-08 | — | — | US | claimed |
| EP-1294775-A1 | METHOD FOR THE PRODUCTION OF A POLYMERISATION REACTION PRODUCT | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-1294786-A2 | USE OF A POLYMER REACTION PRODUCT | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-1144470-A3 | THERMALLY STABLE POLYETHERAMINES | THE DOW CHEMICAL COMPANY (US) | 2002-03-13 | — | — | EP | claimed |
| WO-2000001750-A2 | THERMALLY STABLE POLYETHERAMINES | THE DOW CHEMICAL COMPANY (US) | 2000-01-13 | — | — | WO | claimed |
| US-5962093-A | Thermally stable polyetheramines | THE DOW CHEMICAL COMPANY (US) | 1999-10-05 | — | — | US | claimed |
| WO-1999023134-A1 | HYDROXY ETHER POLYMERS AS THERMOPLASTIC BARRIER RESINS | THE DOW CHEMICAL COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999020673-A1 | THERMALLY STABLE POLYETHERAMINES | THE DOW CHEMICAL COMPANY (US) | 1999-04-29 | — | — | WO | claimed |
| US-5808155-A | HYDROXY COMPOUND | RICOH COMPANY, LTD. (JP) | 1998-09-15 | — | — | US | claimed |
| US-5686551-A | DIHYDROXYSTILBENES, DIGLYCIDYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 1997-11-11 | — | — | US | claimed |
| EP-0460994-B1 | Method and apparatus to make evident one or more shocks received by a substrate | HUTCHINSON SA (FR) | 1995-03-15 | — | — | EP | claimed |
| EP-0579743-A1 | DIAMINO-ALPHA-ALKYLSTILBENES | THE DOW CHEMICAL COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| US-5242830-A | Detection of impact with fluorescent indicators by embedding microcapsules and releasing | HUTCHINSON (FR) | 1993-09-07 | — | — | US | claimed |
| EP-0460994-A1 | Method and apparatus to make evident one or more shocks received by a substrate | HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) | 1991-12-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170306-A1 | Use of polymeric reaction product | OXSR1, OGFR, CBR1 | ESR1 1465/4885ESR2 956/4885ALDH1A1 2250/4885 |
| US-20130280245-A1 | 3-Aryl-6-aryl-[1,2,4]triazolo[4,3-alpha]pyridines as Inhibitors of Cell Proliferation and the Use Thereof | MKI67, CCNI, CCNA1 | ESR1 1537/4885ESR2 370/4885ALDH1A1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.