Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 4/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910279 | 0.90 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25911790 | 0.89 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910178 | 0.88 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25913293 | 0.88 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910288 | 0.88 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910037 | 0.88 | CSF1R (0.50) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910302 | 0.87 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910294 | 0.86 | CSF1R (0.55) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25912060 | 0.86 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25911894 | 0.85 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |