Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25911790 | 0.90 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910028 | 0.88 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910302 | 0.86 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25911894 | 0.86 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25912060 | 0.86 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910037 | 0.85 | CSF1R (0.50) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910551 | 0.85 | CSF1R (0.49) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910683 | 0.85 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910026 | 0.85 | CSF1R (0.50) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25910568 | 0.84 | CSF1R (0.55) | CSF1RPDGFRAPDGFRBLCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |