Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.57 |
| ▸ | HTR1D | P28221 | 2/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151410 | 1.00 | HTR2A (0.57) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL1177374 | 1.00 | HTR2A (0.57) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL5155794 | 0.88 | HTR2A (0.57) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL5150887 | 0.88 | HTR2A (0.57) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL4601805 | 0.88 | HTR2A (0.57) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL30888859 | 0.84 | HTR2C (0.71) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL6710624 | 0.84 | HTR2C (0.71) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL10408386 | 0.84 | HTR2C (0.71) | HTR2AHTR1DSCN9AHTR2CHTR1A | |
| SCHEMBL24913231 | 0.83 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL1120488 | 0.83 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713325-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713325-B2 | Antitumoral compounds | TP53, TOP1, MCL1 | HTR2A 4762/4885HTR1D 4565/4885SCN9A 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.