Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.70 |
| ▸ | HTR2C | P28335 | 5/20 | 0.70 |
| ▸ | HTR2B | P41595 | 4/20 | 0.70 |
| ▸ | HTR1A | P08908 | 3/20 | 0.70 |
| ▸ | HTR1D | P28221 | 3/20 | 0.70 |
| ▸ | HTR1B | P28222 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | HTR1E | P28566 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811419 | 1.00 | HTR2A (0.70) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL1120488 | 1.00 | HTR2A (0.70) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL27220697 | 0.89 | HTR2A (0.66) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL24913225 | 0.89 | HTR2A (0.66) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL19067627 | 0.87 | HTR2A (0.61) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL25913471 | 0.84 | HTR2A (0.63) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL699380 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL5151410 | 0.83 | HTR2A (0.57) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL1177374 | 0.83 | HTR2A (0.57) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL25910591 | 0.83 | HTR2A (0.57) | HTR2AHTR2CHTR2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| CN-117813288-A | Arylamino derivative estrogen receptor modulator and use thereof | 西藏海思科制药有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230295190-A1 | Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof | TAE LIFE SCIENCES LLC | 2023-09-21 | — | — | US | disclosed |
| WO-2023284837-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | 四川海思科制药有限公司 | 2023-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | GPER1, ESR1, ESRRA | HTR2A 421/4885HTR2C 316/4885HTR2B 360/4885 |
| US-20230295190-A1 | Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof | BCAT2, BCAT1, SLC1A5 | HTR2A 2478/4885HTR2C 4510/4885HTR2B 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.