Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910633 | 1.00 | MAPT (0.55) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL25910667 | 0.90 | MAPT (0.55) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL25910627 | 0.90 | MAPT (0.55) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL30130055 | 0.89 | NPSR1 (0.50) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL23127160 | 0.88 | MAPT (0.57) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL29380695 | 0.88 | MAPT (0.57) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL25730436 | 0.88 | MAPT (0.57) | MAPTSMN1; SMN2TACR1HDAC3HDAC4 | |
| SCHEMBL21466805 | 0.87 | HTR1A (0.52) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21466568 | 0.87 | HTR1A (0.52) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24702206 | 0.87 | HTR1A (0.52) | TACR1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713325-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713325-B2 | Antitumoral compounds | TP53, TOP1, MCL1 | MAPT 4519/4885SMN1; SMN2 2847/4885TACR1 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.