⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241848 | 0.74 | — | — | |
| SCHEMBL3401573 | 0.71 | — | — | |
| SCHEMBL3401569 | 0.71 | — | — | |
| SCHEMBL711958 | 0.69 | — | — | |
| SCHEMBL10621661 | 0.68 | — | — | |
| SCHEMBL4486098 | 0.68 | — | — | |
| SCHEMBL24200274 | 0.67 | — | — | |
| SCHEMBL16519774 | 0.67 | — | — | |
| SCHEMBL19252586 | 0.67 | — | — | |
| SCHEMBL24200120 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |