Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179749 | 0.86 | RELA (0.74) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL1179750 | 0.86 | RELA (0.74) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL29673932 | 0.86 | RELA (0.74) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL16105653 | 0.82 | RELA (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL16105651 | 0.82 | RELA (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL16105706 | 0.82 | RELA (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL21847980 | 0.82 | PTGS1 (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL1795130 | 0.82 | PTGS1 (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL1795132 | 0.82 | PTGS1 (0.69) | RELAPTGS1PTGS2ALOX5NFE2L2 | |
| SCHEMBL18589848 | 0.81 | RELA (0.62) | RELAPTGS1PTGS2NFE2L2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116851-B1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INST FOR BIOLOGICAL STUDI (US) | 2023-07-26 | — | — | EP | disclosed |