Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 6/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910826 | 1.00 | MEN1 (0.46) | MEN1KMT2ATP53ALDH1A1DRD2 | |
| SCHEMBL25320578 | 0.82 | DYRK1A (0.37) | TP53ALDH1A1UBE2MDCUN1D1CYP3A4 | |
| SCHEMBL29081218 | 0.82 | KMT2A (0.56) | MEN1KMT2ATP53ALDH1A1DRD2 | |
| SCHEMBL13202810 | 0.79 | KMT2A (0.63) | MEN1KMT2ATP53ALDH1A1DRD2 | |
| SCHEMBL2566803 | 0.78 | UBE2M (0.46) | MEN1KMT2ATP53ALDH1A1UBE2M | |
| SCHEMBL19781780 | 0.78 | MEN1 (0.53) | MEN1KMT2ATP53ALDH1A1DRD2 | |
| SCHEMBL25322014 | 0.75 | CYP2D6 (0.33) | CYP3A4 | |
| SCHEMBL25322002 | 0.75 | CYP2D6 (0.33) | CYP3A4 | |
| SCHEMBL30551275 | 0.75 | CYP2D6 (0.33) | CYP3A4 | |
| SCHEMBL30551626 | 0.75 | SNCA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |