Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326867 | 0.90 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL25916845 | 0.85 | PRMT5 (0.37) | PRMT5WDR77CD38 | |
| SCHEMBL25327306 | 0.82 | PRMT5 (0.47) | PRMT5WDR77 | |
| SCHEMBL25327519 | 0.82 | PRMT5 (0.47) | PRMT5WDR77 | |
| SCHEMBL25327312 | 0.82 | PRMT5 (0.47) | PRMT5WDR77 | |
| SCHEMBL25327081 | 0.78 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL25329073 | 0.77 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL25916942 | 0.76 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL25326154 | 0.75 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL25325556 | 0.75 | PRMT5 (0.44) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |