Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.51 |
| ▸ | FLT3 | P36888 | 5/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910030 | 0.87 | CSF1R (0.70) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25912095 | 0.83 | LCK (0.42) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911790 | 0.79 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25912135 | 0.78 | CSF1R (0.74) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910031 | 0.77 | CSF1R (0.72) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911716 | 0.76 | CSF1R (0.48) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911604 | 0.74 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL31741098 | 0.74 | CSF1R (0.82) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25319458 | 0.74 | CSF1R (0.52) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25912706 | 0.72 | CSF1R (0.43) | CSF1RPDGFRAFLT3PDGFRBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |