Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912096 | 0.83 | CSF1R (0.51) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25912094 | 0.81 | CSF1R (0.43) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25910030 | 0.79 | CSF1R (0.70) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25911644 | 0.74 | CSF1R (0.47) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25317059 | 0.74 | PDGFRB (0.47) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25911715 | 0.72 | CSF1R (0.43) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25911369 | 0.71 | CSF1R (0.45) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25911557 | 0.70 | PDGFRB (0.42) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25911603 | 0.69 | CSF1R (0.48) | LCKCSF1RPDGFRBKITCYP2C9 | |
| SCHEMBL25319475 | 0.68 | CSF1R (0.47) | LCKCSF1RPDGFRBKITCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |