Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153967 | 0.88 | ALDH1A1 (0.48) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL8073461 | 0.88 | ALDH1A1 (0.48) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL8071185 | 0.88 | ALDH1A1 (0.48) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL8082859 | 0.86 | ALDH1A1 (0.47) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL8075110 | 0.85 | ALDH1A1 (0.46) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL8144919 | 0.84 | ALDH1A1 (0.45) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL10289297 | 0.81 | KDM4E (0.44) | ALDH1A1HIF1AKDM4EHSD17B10PARP1 | |
| SCHEMBL12589464 | 0.80 | BRD4 (0.56) | EIF4A3ALDH1A1HIF1AKDM4EHSD17B10 | |
| SCHEMBL18596058 | 0.78 | EIF4A3 (0.53) | EIF4A3ALDH1A1KDM4EDAOMAPT | |
| Bromide SCHEMBL31571064 | 0.78 | PARP1 (0.42) | ALDH1A1HIF1AKDM4EHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134647-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 优领医药科技(香港)有限公司 | 2023-07-20 | — | — | WO | disclosed |