Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086912 | 0.80 | TYR (0.54) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL2086915 | 0.80 | TYR (0.54) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL367595 | 0.79 | TYR (0.58) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL23918549 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL30075786 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL8073887 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| Methane SCHEMBL11025053 | 0.77 | TYR (0.56) | TYRMAPK1KDM4EALDH1A1GRIN2D | |
| SCHEMBL104124 | 0.76 | TYR (0.58) | TYRMAPK1KDM4EALDH1A1PTGS1 | |
| SCHEMBL11458762 | 0.76 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL139407 | 0.76 | TYR (0.61) | TYRMAPK1KDM4EALDH1A1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2932973-B1 | FORMULATIONS FOR USE IN THE TREATMENT OF SKIN CONDITIONS | SOLIGENIX INC (US) | 2020-04-01 | — | — | EP | disclosed |
| EP-2571507-B1 | FORMULATIONS AND METHODS OF TREATMENT OF SKIN CONDITIONS | SOLIGENIX INC (US) | 2017-01-04 | — | — | EP | disclosed |
| EP-2932973-A1 | FORMULATIONS FOR USE IN THE TREATMENT OF SKIN CONDITIONS | Soligenix, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| US-20130211371-A1 | FORMULATIONS AND METHODS OF TREATMENT OF SKIN CONDITIONS | HY BIOPHARMA, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2571507-A1 | FORMULATIONS AND METHODS OF TREATMENT OF SKIN CONDITIONS | HY Biopharma Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011139558-A1 | FORMULATIONS AND METHODS OF TREATMENT OF SKIN CONDITIONS | HY BIOPHARMA, INC. (US) | 2011-11-10 | — | — | WO | disclosed |