Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | CSF1R | P07333 | 18/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.43 |
| ▸ | FLT3 | P36888 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25911297 | 0.87 | KDR (0.49) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL25910156 | 0.77 | CSF1R (0.74) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL2410569 | 0.75 | KDM4E (0.47) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL16029051 | 0.75 | CSF1R (0.46) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL28341082 | 0.73 | CSF1R (0.49) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL14447156 | 0.73 | FYN (0.58) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL2415726 | 0.73 | KDR (0.52) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL16561327 | 0.72 | CCR1 (0.58) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL23888616 | 0.72 | KDR (0.54) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL30086949 | 0.71 | CSF1R (0.54) | KDRCSF1RPDGFRAPDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |