Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22088125 | 0.72 | — | — | |
| SCHEMBL10144670 | 0.71 | HPGD (0.39) | SIGMAR1ALDH1A1RECQLKMT2A | |
| SCHEMBL25957622 | 0.70 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL4268740 | 0.69 | SMYD3 (0.38) | SIGMAR1 | |
| SCHEMBL4268735 | 0.69 | SMYD3 (0.38) | SIGMAR1 | |
| SCHEMBL4268743 | 0.69 | SMYD3 (0.38) | SIGMAR1 | |
| SCHEMBL22087602 | 0.69 | — | — | |
| SCHEMBL23573398 | 0.64 | MME (0.40) | ALDH1A1KMT2A | |
| SCHEMBL23573400 | 0.64 | MME (0.40) | ALDH1A1KMT2A | |
| SCHEMBL25914683 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |