SCHEMBL25913015

SCHEMBL25913015

CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCC[C@@H]2C(O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 10/20 1.00
▸ PGR P06401 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21024922 1.00 NR3C1 (1.00) NR3C1PGR
SCHEMBL12956251 1.00 NR3C1 (1.00) NR3C1PGR
SCHEMBL1880230 1.00 NR3C1 (1.00) NR3C1PGR
SCHEMBL10116155 0.96 NR3C1 (1.00) NR3C1PGR
SCHEMBL12956236 0.96 NR3C1 (1.00) NR3C1PGR
SCHEMBL18017599 0.93 NR3C1 (0.93) NR3C1PGR
SCHEMBL12956166 0.92 NR3C1 (1.00) NR3C1PGR
SCHEMBL11995501 0.92 NR3C1 (1.00) NR3C1PGR
SCHEMBL12956177 0.91 NR3C1 (0.86) NR3C1PGR
SCHEMBL13581501 0.91 NR3C1 (1.00) NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256470-B1 METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES DANA FARBER CANCER INST INC (US) 2023-07-26 — — EP disclosed
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