SCHEMBL25913654

SCHEMBL25913654

CCc1ccc(C(O)NC2CCC(=O)NC2=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.50
▸ DDB1 Q16531 16/20 0.50
▸ IKZF3 Q9UKT9 1/20 0.40
▸ HTT P42858 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23513440 0.82 CRBN (0.57) CRBNDDB1IKZF3
SCHEMBL24678275 0.77 DDB1 (0.74) CRBNDDB1
SCHEMBL25802984 0.75 CRBN (0.70) CRBNDDB1IKZF3
SCHEMBL24938226 0.75 CRBN (0.43) CRBNDDB1IKZF3
SCHEMBL21214936 0.73 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL23799091 0.70 CRBN (0.44) CRBNDDB1IKZF3
SCHEMBL25091706 0.70 DDB1 (0.61) CRBNDDB1
SCHEMBL20325539 0.69 CRBN (0.57) CRBNDDB1
SCHEMBL23551677 0.69 CRBN (0.49) CRBNDDB1IKZF3POLB
SCHEMBL23551779 0.69 CRBN (0.49) CRBNDDB1IKZF3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023115149-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
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