SCHEMBL25913665

SCHEMBL25913665

c1ccc(-c2cc(-c3ccccc3)c(OCCn3cccc3)c(-c3ccccc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.37
TUBB1 Q9H4B7 1/20 0.36
TBXAS1 P24557 1/20 0.36
BACE1 P56817 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 2/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HTR7 P34969 1/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SLC6A9 P48067 1/20 0.33
IKBKB O14920 1/20 0.33
GSTP1 P09211 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21242380 0.83 PTGS1 (0.37) BACE1MEN1KMT2AHTR7ALDH1A1
SCHEMBL21242381 0.71 PTGDR2 (0.40) BACE1MEN1KMT2AALDH1A1NPC1
SCHEMBL5988287 0.68 PTPN1 (0.55) KMT2A
SCHEMBL19976280 0.68 PTGS1 (0.39) BACE1SMN1; SMN2HTR7KDM4EALDH1A1
SCHEMBL2096573 0.65 PDE4B (0.55) BACE1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL27862699 0.65 PTPN1 (0.41) BACE1MEN1KMT2AHTTLMNA
SCHEMBL29065606 0.65 PTPN1 (0.41) BACE1MEN1KMT2AHTTLMNA
SCHEMBL2096572 0.65 PTPN1 (0.41) BACE1MEN1KMT2AHTTLMNA
SCHEMBL27831222 0.65 TDP1 (0.54) MEN1KMT2ALMNASMN1; SMN2ALDH1A1
SCHEMBL3121239 0.64 PTPN1 (0.40) BACE1MEN1KMT2AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377465-B1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI INC (US) 2023-08-02 EP disclosed