SCHEMBL25914432

SCHEMBL25914432

CCCCC(CC)CN(CC(CC)CCCC)C(=O)CCCCCBr

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
CA2 P00918 2/20 0.42
ALDH1A1 P00352 5/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
FFAR4 Q5NUL3 1/20 0.36
FFAR1 O14842 1/20 0.36
LMNA P02545 2/20 0.35
FAAH O00519 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13630663 0.92 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMCA2
SCHEMBL11013966 0.91 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMCA2
SCHEMBL9307290 0.91 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMCA2
SCHEMBL2487834 0.91 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMCA2
SCHEMBL9306605 0.91 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMCA2
SCHEMBL12640148 0.91 CA2 (0.50) CYP3A4TSHRTDP1ATMCA2
SCHEMBL16697003 0.89 CA2 (0.46) CYP3A4TSHRTDP1ATMCA2
SCHEMBL10623771 0.89 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMCA2
SCHEMBL11775210 0.86 CYP3A4 (0.44) CYP3A4TSHRTDP1ATMCA2
SCHEMBL15153778 0.84 CA2 (0.50) CYP3A4TSHRTDP1ATMCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295075-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2023-09-21 US disclosed
US-20230295075-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2023-09-21 US disclosed
WO-2023114943-A2 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295075-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS PHOSPHO1, SGMS1, NPC1 CYP3A4 2030/4885TSHR 2371/4885TDP1 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.