Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24728724 | 1.00 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL2058589 | 1.00 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL2058490 | 1.00 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL2058499 | 1.00 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL2058520 | 0.97 | DNM1 (0.46) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL4481993 | 0.94 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL2058618 | 0.94 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL9397584 | 0.94 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL4886759 | 0.94 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL9580812 | 0.94 | DNM1 (0.50) | DNM1LMNATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114943-A2 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-06-22 | — | — | WO | disclosed |