Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320238 | 0.86 | DGAT1 (0.32) | DGAT1MAPT | |
| SCHEMBL25321588 | 0.81 | CYP17A1 (0.33) | DGAT1MAPT | |
| SCHEMBL25319926 | 0.80 | DGAT1 (0.33) | DGAT1MAPT | |
| SCHEMBL25326471 | 0.76 | MAPKAPK2 (0.33) | DGAT1 | |
| SCHEMBL25860359 | 0.75 | CYP3A4 (0.38) | DGAT1SMN1; SMN2 | |
| SCHEMBL20129641 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL25324134 | 0.71 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25048610 | 0.70 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25319549 | 0.70 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL25321169 | 0.70 | MAPT (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |