Ganciclovir

Ganciclovir

SCHEMBL25915

Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1.[NaH]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.98
MEN1 O00255 2/20 0.98
KMT2A Q03164 2/20 0.98
ALDH1A1 P00352 1/20 0.98
LMNA P02545 1/20 0.98
CYP3A4 P08684 1/20 0.98
NFKB1 P19838 1/20 0.98
VCP P55072 1/20 0.98
SMN1; SMN2 Q16637 1/20 0.98
HIF1A Q16665 1/20 0.98
PDE3A Q14432 1/20 0.71
PNP P00491 7/20 0.68
USP2 O75604 1/20 0.68
TSHR P16473 1/20 0.68
EDNRA P25101 1/20 0.68
HTR2A P28223 1/20 0.68
RECQL P46063 1/20 0.68
HBB P68871 1/20 0.68
HSD17B10 Q99714 1/20 0.68
HPRT1 P00492 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ganciclovir SCHEMBL10901311 0.99 BLM (0.95) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL3378434 0.99 BLM (0.95) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL3033 0.99 BLM (1.00) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL2160505 0.99 BLM (1.00) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481436 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481442 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL11093368 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10899902 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10901635 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL1242615 0.98 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2837 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
CN-112274511-B Quinoline derivatives for the treatment of graft versus host disease 正大天晴药业集团股份有限公司 2024-04-02 CN claimed
US-20240041861-A1 COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS NED BIOSYSTEMS INC (US) 2024-02-08 US claimed
US-20230346697-A1 ANTIMICROBIAL AND ANTI-INFLAMMATORY COMPOSITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-11-02 US claimed
EP-4262812-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS Southern Research Institute (US) 2023-10-25 EP claimed
CN-113149987-B Preparation method of injection-grade ganciclovir 南京杏药原医药科技开发有限公司 2023-09-15 CN claimed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO claimed
CN-219072940-U Condensation reaction kettle for preparing ganciclovir sodium 安徽普利药业有限公司 2023-05-26 CN claimed
JP-2001512354-A 2001-08-21 JP claimed
WO-2001056547-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS YOO SEO HONG (US) 2001-08-09 WO claimed
US-6096070-A Coated implantable medical device MED INSTITUTE INC. (US) 2000-08-01 US claimed
EP-0968013-A1 COATED IMPLANTABLE MEDICAL DEVICE Cook Incorporated (US) 2000-01-05 EP claimed
US-5873904-A Silver implantable medical device COOK INCORPORATED (US) 1999-02-23 US claimed
WO-1998036784-A1 COATED IMPLANTABLE MEDICAL DEVICE COOK INCORPORATED (US) 1998-08-27 WO claimed
WO-1998017331-A1 SILVER IMPLANTABLE MEDICAL DEVICE COOK INCORPORATED (US) 1998-04-30 WO claimed
EP-0779820-A1 BIOADHESIVE-WOUND HEALING COMPOSITION WARNER-LAMBERT COMPANY (US) 1997-06-25 EP claimed
EP-0747069-A2 Implantable medical device Cook Incorporated (US) 1996-12-11 EP claimed
WO-1996006640-A1 BIOADHESIVE-WOUND HEALING COMPOSITION WARNER-LAMBERT COMPANY (US) 1996-03-07 WO claimed