Ganciclovir

Ganciclovir

SCHEMBL3033

Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
CYP3A4 P08684 1/20 1.00
NFKB1 P19838 1/20 1.00
VCP P55072 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
HIF1A Q16665 1/20 1.00
PDE3A Q14432 1/20 0.72
PNP P00491 7/20 0.70
USP2 O75604 1/20 0.70
TSHR P16473 1/20 0.70
EDNRA P25101 1/20 0.70
HTR2A P28223 1/20 0.70
RECQL P46063 1/20 0.70
HBB P68871 1/20 0.70
HSD17B10 Q99714 1/20 0.70
HPRT1 P00492 6/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ganciclovir SCHEMBL2160505 1.00 BLM (1.00) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10899902 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481442 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL2433042 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481436 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL1242615 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL25915 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL11093368 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10901635 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL11121521 0.99 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 81613 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144816-A1 COMPOSITIONS AND METHODS FOR TREATING DEMENTIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-28 US claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4748448-A2 USE OF MARIBAVIR FOR THE TREATMENT OF AND TREATMENT REGIMENS THEREOF Takeda Pharmaceutical Company Limited (JP) 2026-05-27 EP claimed
US-12637688-B2 DNA construct for diagnosing and treating cancer CNCURE BIOTECH INC. (KR) 2026-05-26 US claimed
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US claimed
WO-2026107113-A1 MODIFIED CELLS FOR PROGRAMMING EXTRA ENVELOPED VIRUSES (EEVs) AND THEIR USE FOR PRODUCING THE EEVs, THE PROGRAMMED EEVs AND USES THEREOF CALIDI BIOTHERAPEUTICS (NEVADA), INC. (US) 2026-05-21 WO claimed
WO-2026107010-A1 MODULATION OF GENE EXPRESSION FOR GENE THERAPY THE METHODIST HOSPITAL (US) 2026-05-21 WO claimed
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 EP claimed
US-12631653-B2 Methods for diagnosing and treating uveitis THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-19 US claimed
WO-2025136820-A9 POLY-ANTIGEN CYTOKINE-RECEPTOR COMPLEXES (PACCS), COMPOSITIONS, AND METHODS OF USE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2026-05-15 WO claimed
EP-0066208-B1 9-(1,3-DIHYDROXY-2-PROPOXYMETHYL)-GUANINE AS ANTIVIRAL AGENT SYNTEX (U.S.A.) INC. (US) 1985-10-02 EP claimed
EP-0135713-A2 Antiviral combinations THE WELLCOME FOUNDATION LIMITED (GB) 1985-04-03 EP claimed
US-4507305-A 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent SYNTEX (U.S.A.) INC. (US) 1985-03-26 US claimed
EP-0119757-A2 Guanine derivatives, compositions containing them, and their anti-viral use SYNTEX (U.S.A.) INC. (US) 1984-09-26 EP claimed
US-4462986-A INTERFERON AND 9-((2-HYDROXY-1-(HYDROXYMETHYL)-ETHOXY)METHYL)GUANINE ENS BIO LOGICALS, INC. (CA) 1984-07-31 US claimed
EP-0109234-A1 Compositions comprising interferon and their therapeutic use SYNTEX (U.S.A.) INC. (US) 1984-05-23 EP claimed
EP-0105486-A2 1-Monophosphate esters, 1,3-bisphosphate esters and cyclic phosphate esters of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as antiviral agents SYNTEX (U.S.A.) INC. (US) 1984-04-18 EP claimed
US-4423050-A 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent SYNTEX (U.S.A.) INC. (US) 1983-12-27 US claimed
EP-0066208-A1 9-(1,3-Dihydroxy-2-propoxymethyl)-guanine as antiviral agent SYNTEX (U.S.A.) INC. (US) 1982-12-08 EP claimed
US-4355032-A 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent SYNTEX (U.S.A.) INC. (US) 1982-10-19 US claimed