Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.68 |
| ▸ | CA9 | Q16790 | 9/20 | 0.68 |
| ▸ | CA1 | P00915 | 8/20 | 0.68 |
| ▸ | STS | P08842 | 8/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451359 | 0.98 | CA2 (0.70) | CA2CA9CA1STSCA12 | |
| SCHEMBL9451263 | 0.82 | CA2 (1.00) | CA2CA9CA1STS | |
| Phenylsulfamate SCHEMBL3213804 | 0.82 | CA2 (0.95) | CA2CA9CA1STSCA12 | |
| SCHEMBL7263619 | 0.80 | CA2 (1.00) | CA2CA9CA1STSCA12 | |
| Phenylsulfamate SCHEMBL605969 | 0.80 | CA2 (1.00) | CA2CA9CA1STSCA12 | |
| SCHEMBL19568049 | 0.79 | CA1 (0.44) | CA2CA9CA1STS | |
| SCHEMBL6938292 | 0.79 | CA2 (0.47) | CA2CA9CA1CA12 | |
| SCHEMBL30195034 | 0.79 | CA2 (0.47) | CA2CA9CA1CA12 | |
| SCHEMBL4684800 | 0.78 | PTPN1 (0.47) | CA2CA9CA1 | |
| Phenylsulfamate SCHEMBL4592853 | 0.78 | CA2 (0.95) | CA2CA9CA1STSCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |