Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325690 | 0.92 | MGLL (0.33) | MGLL | |
| SCHEMBL30553190 | 0.92 | MGLL (0.33) | MGLL | |
| SCHEMBL30553185 | 0.86 | MGLL (0.36) | ADRA2CMGLLSPR | |
| SCHEMBL25325185 | 0.86 | MGLL (0.36) | ADRA2CMGLLSPR | |
| SCHEMBL25323768 | 0.84 | MGLL (0.35) | ADRA2CMGLLSPRPARP1 | |
| SCHEMBL25324553 | 0.80 | MGLL (0.36) | ADRA2CMGLLSPR | |
| SCHEMBL25328437 | 0.80 | MGLL (0.36) | ADRA2CMGLLSPR | |
| SCHEMBL25326102 | 0.80 | MGLL (0.36) | ADRA2CMGLLSPR | |
| SCHEMBL25325214 | 0.79 | MGLL (0.34) | MGLL | |
| SCHEMBL30553259 | 0.79 | MGLL (0.34) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |